The danger of administering methylene blue by non-intravenous paths (such as dental tablets or by regional treatment) or in intravenous doses much lower than 1 mg/kg with PAXIL is uncertain. In 1 professional test, the efficiency of PAXIL was shown in individuals dosed in a range of 20 to 50 mg/day. Subgroup analyses did not suggest that there were any sort of distinctions in therapy results as a function of age or gender.
In this research study, people obtaining paroxetine experienced a mean reduction of roughly 7 levels on the YBOCS total rating, which was dramatically better than the mean reduction of about 4 factors in placebo‑treated patients.
The suggested beginning dose and the recognized efficient dose is 20 mg/day. Reports of raised theophylline levels associated with treatment with Paxil have been reported. In the inventories that comply with, reported unfavorable occasions were categorized utilizing a standard COSTART‑based Dictionary jargon. Such tracking should consist of day-to-day monitoring by caregivers and households. Research 1, a dose-range finding research study where patients were treated with set dosages of 20, 40, or 60 milligrams of paroxetine/day demonstrated that everyday dosages of paroxetine 40 and 60 mg are reliable in the therapy of OCD.